The excess production of the "pyrrole" compound in the body, and the nutrient deficiencies and metabolic or biochemical dysfunctions of Pyrrole Disorder, are known to cause many symptoms and conditions.
There are many other conditions which are commonly found in those with Pyrrole Disorder which are not as well known, but can be caused by and/or associated with PD or having elevated pyrrole compounds (HPL) in the urine, including all those shown in the attached diagram.
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Some of these conditions may be a surprise to some, including Lyme disease, Parkinson's disease, and the Autism spectrum disorders, especially ADHD, and more. I have seen many similarities of ADHD with Pyrrole Disorder, or many people being diagnosed with ADHD as well as Pyrrole Disorder, suggesting that they are perhaps one and the same condition. This information and graphic was based on a published scientific article on the pyrrole compounds being found in 80% of patients with chronic Lyme disease (Forsgren, 2009) and these other conditions too.

​This gives some hope and additional treatment options for people with Lyme disease, ADHD, and other conditions shown in the graphic.
 
Reference:
Forsgren, S. (2009). Kryptopyrroluria (aka Hemopyrrollactaminuria): A major piece of the puzzle in overcoming chronic Lyme Disease. Explore, 18 (6), 1-7. 

​What is Pyrrole Disorder? It is a little known condition which can be initiated from severe or chronic stress or emotional trauma, which then triggers a genetic predisposition for excess production of a compound called HPL, which causes nutrient deficiencies. Because food nutrients are needed for a lot of functions and processes in your body, a deficiency in more than one nutrient will cause many seemingly separate symptoms. Specific nutrient deficiencies cause symptoms which result in Pyrrole Disorder (PD).
Many GPs and doctors don't know about or recognise PD, as it just looks like you have a bunch of fairly common symptoms, including:

• headaches and migraines
• digestive complaints - constipation, reflux, bloating
• poor tolerance to stress
• depression and/or anxiety
• sleep issues (can't get to sleep, or interrupted sleep)
• poor immune system and lots of infections
• allergies and intolerances to foods or environmental substances
• sensitivity to light, sounds, tastes
• and many more symptoms (as shown in the above picture).
  

 You don't need to have all these symptoms, but having more increases the likelihood. When I see some or all of these symptoms together as I do in many clients, I look for the root causes for them all. I also use a screening questionnaire, analysis of pathology results, and specific pyrrole tests.
Pyrroles is nothing to be worried about! If anything it is great to have this diagnosis, as it is very easily treatable mainly with nutritional medicine! I've seen the condition in children as well as adults over 60 years of age, and it's always a relief to finally have an answer to their health issues!
​Pyrroles causes nutritional deficiencies mainly in zinc and vitamin B6, but also of lesser deficiencies in other B-vitamins, magnesium, omega-6 fats and others. Multiple deficiencies lead to all of the symptoms above, and more. Pyrroles is very frequently seen running in families across multiple generations. It is VERY common in those with Irish and Celtic family history, and the reasons for this are unknown.
Some research shows that PD itself is very commonly linked to, and probably even a cause of bipolar disorder, schizophrenia, some autism disorders and other neurological and behavioural conditions.
If you recognise many of the above symptoms (in the picture) in yourself, your children, or other people you know, it would be a good idea to see if Pyrroles may be the cause! I have seen substantial reductions of symptoms with the nutritional medicine treatment for this condition! And those who have improved feel like they have their life (and health) back again!